Charles Esther
In today’s high-performance culture, one molecule is generating buzz among wellness elites — NAD.
Short for nicotinamide adenine dinucleotide, NAD is a naturally occurring compound vital to cell health, energy production, and metabolic function.
Though our bodies produce NAD, levels begin to decline with age — some studies indicate this starts in the mid-40s — which can reduce the cells’ ability to repair and regenerate efficiently.
That’s where NAD infusions come in.
Discovered over a century ago, NAD has become a recent darling of the longevity world thanks to advancements in biotechnology.
Just like GLP-1 drugs such as Ozempic made their way from medical obscurity to celebrity staples, NAD is entering the mainstream.
Now, NAD+ infusions — said to boost immunity, energy, and even appearance — are being promoted by celebrities including Hailey Bieber, Kendall Jenner, Jennifer Aniston, and Joe Rogan, as well as biohackers like Dave Asprey and athletes like Kevin Love.
Love, an NBA All-Star, swears by monthly IV drips to maintain peak performance, calling it “a longevity hack to the max.”
He reports increased cognitive clarity and energy after consistent use.
These infusions are now more widely available, popping up in med spas and wellness centers offering both luxury packages and express services.
Trying an NAD Infusion Firsthand
Wellness IVs are not just trendy — they’re part of a broader shift toward preventative, performance-focused self-care.
To experience it for myself, I visited Niagen Biosciences, a company led by Hollywood producer Rob Fried that specializes in NAD innovations.
After entering their suite at the Hudson Yards Equinox hotel, I was administered a 125 mg pharmaceutical-grade NAD IV drip.
The cost? Between $799 and $1,500 depending on dosage.
I underwent a quick telehealth consultation to confirm I was a suitable candidate, and then the infusion began.
Despite anticipating potential side effects like headaches or digestive discomfort, I felt little during the process.
I lounged for 45 minutes with a view of the Hudson River while the IV slowly delivered one of today’s most coveted longevity treatments.
Do NAD Infusions Work? What the Experts Say
To understand what NAD infusions actually do, I spoke with Charles Brenner, chief scientific officer of Niagen Biosciences and a leading expert on NAD research.
He explained that while healthy individuals may not feel an immediate transformation, NAD helps repair muscles, reduce inflammation, and improve skin and hair health.
Some users report fewer colds and quicker recovery from illness or injury.
According to Brenner, boosting NAD levels essentially lets the body behave as if it were much younger — more resilient and quicker to heal.
Promising research also suggests that NAD may support long-term health, potentially protecting the brain from age-related diseases like Parkinson’s and enhancing heart and liver function.
Not All NAD Products Are Equal
It’s important to note that NAD can’t be absorbed directly through supplements.
Instead, supplements use precursors such as NR (nicotinamide riboside) or NMN (nicotinamide mononucleotide), which convert to NAD in the body.
Niagen’s formulation uses a patented version of NR backed by scientific testing for safety and potency.
However, the wider supplement market lacks strict regulation, and many products contain unproven or misleading ingredients.
Anyone considering NAD treatment — especially individuals with health conditions or those pregnant — should consult a doctor first.
Some interactions, especially with insulin or kidney function, require caution.
What It Felt Like Post-Infusion
While I didn’t notice drastic effects during the treatment, I felt notably more energetic afterwards — similar to drinking a strong coffee.
There was a slight warmth in my body, which is common with NAD drips.
Some users report intense heat and flushed skin, though I experienced only mild warmth without discomfort.
Several hours later, I still felt mentally alert and physically refreshed.
While the placebo effect can’t be ruled out, the mood and energy boost were significant enough to challenge my usual skepticism toward wellness fads.
Is NAD Right for Everyone?
At present, NAD infusions are more of a luxury than a necessity.
What used to be a niche treatment is now offered at hundreds of clinics, often within a single lunch break.
Still, cost remains a barrier — ranging from hundreds to over a thousand dollars per session.
For those on a budget, oral supplements are more affordable at around $116 for a 30-day supply.
Fortunately, natural lifestyle habits can also help maintain healthy NAD levels.
Regular exercise, adequate sleep, stress management, and foods like fish, broccoli, and nuts contribute to NAD production.
Conclusion
NAD infusions are fast becoming the wellness trend of choice for elite performers seeking longevity, faster recovery, and enhanced energy.
But for the average person, they remain an expensive, though intriguing, indulgence.
While more research is underway, NAD is clearly a key player in the growing field of bio-optimisation.
For now, focusing on basic wellness habits might offer many of the same benefits — without the price tag.
